Although there are no known side effects or health hazards associated with recommended dosages of saffron preparations in healthy individuals, people with chronic medical conditions should consult with their healthcare professional before taking the herb. In addition, pregnant women should never take saffron, as the herb stimulates uterine contractions and may cause miscarriage.
Saffron can cause severe illness, kidney damage, central nervous system paralysis, and possible death at dosage of 12 g and higher, the symptoms of saffron poisoning include:
· Vomiting
· Uterine bleeding
· Intestinal cramping
· Bloody diarrhea
· Skin hemorrhaging
· Dizziness
· Stupor
· Paralysis
If any of these symptoms occur, the user should discontinue the use of saffron immediately and seek emergency medical assistance.